The public curiosity in terms of uncovering the significance of CBD on human health is rising. The organic chemical compound found within the cannabis indica or cannabis sativa plants interacts with the human physiological system. It may offer a great host of medical advantages, such as relieving symptoms of several medical conditions.
Since CBD contains an insignificant percentage of THC compound that’s responsible for creating a psychoactive high, it is preferred to use for pain relief, stress relief, and other therapeutic effects. Generally, CBD oil is used for yielding therapeutic benefits. The oil can be found by extracting the CBD compound from a cannabis sativa or hemp plant.
As some research confirms CBD oil’s role in easing a few symptoms of ailments, it’s gaining more momentum. Still, how does it work inside the body? Keep on reading to discover the role of CBD in human physiology.
What Exactly is CBD?
CBD or also known as cannabidiol, is one of the hundreds of compounds found in cannabis plants. Each of these compounds tends to play a key role in the endocannabinoid system. However, CBD and THC are the two well-known compounds of cannabis sativa and cannabis indica plants.
CBD is acquired through a variety of extraction methods. The most expensive extraction method is carbon dioxide extraction that separates CBD from the other compounds of the plant. Low temperatures and a highly pressurized environment are created to maximize the extraction during this process.
The compound can be extracted from the stem, leaves, stalk, and flowers of the hemp plants. The resulting compounds influence the human endocannabinoid system. This therapeutic manipulation of the endocannabinoid system may be performed with CBD oil since it’s a potent cannabinoid, and it binds with the receptors to influence the activity.
The Role of CBD Oil Inside of the Body
Research has shown that CBD interacts with the endocannabinoid system in the human body. The endocannabinoid system is the complex biological system discovered back in the 1990s. It regulates major activities like appetite, mood, memory, and sleep. This system is made of endocannabinoids, receptors, and enzymes.
The function of endocannabinoids is opposite to other traditional neurotransmitters. These are more synthesized on demand. It functions as the flow-control mechanism, signaling the presynaptic cell for slowing down and preventing the release of neurotransmitters.
When the endocannabinoid system fails to function properly, it leads to the development of CECD or endocannabinoid deficiency syndrome, where patients experience other medical conditions such as pain, inflammation, depression, PTSD, and more. CBD may be an effective way to deal with CECD and subsequently the list of other ailments.
Medical experts have studied that CBD inhibits FAAH or fatty acid amide hydrolase, an enzyme that is a primary molecule responsible for the breakdown of the endocannabinoids and their recycling process. CBD oil doesn’t impact the endocannabinoid system only but it also exerts other therapeutic actions in the body.
The therapeutic actions exerted by CBD in the body include:
- CBD, along with other cannabinoids, may affect the TRPV1 activation. These receptors regulate pain, inflammation, and body temperature.
- The use of CBD oil may lead to PPAR-gamma activation. These PPAR-gamma receptors assist in the process of removing beta-amyloid plaque, which is a primary and major contributor to Alzheimer’s. This activity of CBD explains why CBD may help patients with Alzheimer’s and schizophrenia.
- Experimental evidence shows that CBD induces antiepileptic and anxiolytic effects by 5-ht1A activation. Taking CBD oil in a higher dosage may lead to 5-ht1A activation that assists in moderating anxiety, appetite, pain, vomiting, and nausea.
- CBD may moderately prevent the adenosine reuptake as it inhibits the equilibrative nucleoside transporter. This explains the significance of CBD oil for inflammation and other autoimmune conditions.
- The GPR55 receptors found in the human brain are responsible for regulating blood pressure, bone density, and other major functions. However, these receptors encourage the cancer cells’ proliferation and increase the chances of developing cancer. CBD may help to turn these cancerous cells off.
- There are glycine receptors in the human system that play a key role in pain proprioception. CBD oil has the potential to influence these receptors and reduce chronic pain and inflammation.
As the endocannabinoids system exists in all mammals, CBD oil may help relieve anxiety, pain, inflammation, and more in humans and other mammals. Although researchers have conducted massive research to understand the influence of CBD oil, the FDA still hasn’t approved the medicinal use of CBD.
Always Buy CBD From Trustworthy Sources
CBD has become one of the essential components of the worldwide medical marijuana community. So far, the majority of the governments have approved the use of CBD derived only from hemp plants. The cultivation of hemp plants is legal as per the 2018 Farm Bill. Yet, the THC compound should be less than 0.03%.
The best CBD companies invest extensively in producing high-quality hemp extracts that contain the legal limit or lower THC while removing all unwanted and toxic compounds. These companies are transparent with lab reports and tests for heavy metals, pesticides, solvents, and microbial contaminants.